Executive Officer of Association of Osaka Prefecture Hospitals
Division Head of Neurosurgery
Director of Spine Center
Clinical Professor, Neurosurgery, Osaka Metropolitan University Graduate School of Medicine
Moriguchi-Ikuno Memorial Hospital Misao Nishikawa, M.D. D.M.Sc. Ph.D.
ADDRESS OF OFFICE
Moriguchi-Ikuno Memorial Hospital 6-17-33 Satanakamachi, Moriguchi City, Osaka 570-0002, Japan Phone: +81-6-6906-1100 Fax: +81-6-6902-9070
EDUCATION
1981 - 1987
Osaka City University, Medical School
1990 - 1994
Graduate and Doctor courses: Neurosurgery, Osaka City University Graduate School of Medicine
Clinical study of Chiari malformation and syringomyelia
Pathogenesis of Chiari malformation: a morphometric study of the posterior cranial fossa
Developmental biology: neural crest cell segregation and migration
POSTGRADUATE TRAINING
1987 – 1989
Internship / Residency Clinical resident, Department of Neurosurgery, Osaka City University, Medical School
1990 – 1994
Graduate School Graduate and Doctor courses: Neurosurgery, Osaka City University Graduate School of Medicine
1997
Scholar for Developmental biotechnology and molecular biology Institute of Neuroscience, University of Oregon,
LICENSES AND CERTIFICATIONS
1987
License, Medical Board of Japan, No. 311509
1993
Certificate, Japanese Board of Neurological surgery, No. 3691
1994
Doctorate of Medical Science and Physiopathology (D.M.Sc. and Ph.D.) Osaka City University Graduate School of Medicine
2004
Teaching board of Japanese Spinal Surgery Society No.33
2018
Teaching board of Japanese Society of Apoplexy Surgery
2018
Teaching board of Japanese Society for Pediatric Neurosurgery
HONORS AND AWARDS
1998
Tsuru Award for the excellent work “Pathogenesis of Chiari malformation” of spinal surgery in Japanese Society of Spinal Surgery
2005
Osaka City Award for the excellent work “Chiari I malformation associated with ventral compression and instability: one-stage posterior ecompression and fusion with a new instrumentation technique” of Osaka City Medical Society.
2010
Award of America and Asia Culture Communication Society of America and Asia Culture Communication in Long Island
2012
Award of Koudoukai Health System for outstanding clinical activity Koudoukai Health System “Fusion in patients with occipito-atlanto-axial instability: management strategy and results”
2020-2021, 2022-2023
The Best Doctor in Japan Teladoc Health
2022-2025
Doctor of Doctors T-PEC
ACADEMIC AND HOSPITAL APPOINTMENTS
1990 – 1994
Medical staff, Department of Neurosurgery, Osaka City University, Medical School
1994 – 1997
Clinical Staff, Department of Neurosurgery, Osaka City General Hospital Teaching staff, Department of Neurosurgery, Osaka City University Graduate School of Medicine
1997 – 2001, September
Chief of Medical Doctor, Department of Neurosurgery, Osaka City General Hospital
2001~2006 September
Assistant Professor, Department of Neurosurgery and Neurophathophysiology, Osaka City University Graduate School of Medicine Division Head of Spine and Stroke, Osaka City University Hospital
2006 September, ~ 2010 March
Research Director The Chiari Institute, Department of Neurosurgery North Shore University Hospital
2010 April~
Chairman of Neurosurgery of Moriguchi-Ikuno memorial hospital Division Head of Spine and Stroke
2013 April ~
Present, Current Position and Academic activity
GRANTS
1992 ~ 1994
Syringomyelia, Neurological and psychiatric disorders 8-5A Japan Health welfare
1995 ~ 1997
Spina Bifida, Neurological and psychiatric disorders 8-5B Japan Health welfare
2010 ~ 2011
“Conquer Chiari and Column of Hope” foundation Principal Investigator of research project titled “Morphometric and volumetric analyses of the posterior cranial fossa in the patients with Chiari malformations”
SCIENTIFIC EXPERTISE
Clinical study in Chiari malformation and syringomyelia #1: Pathophysiological study and Management of Chiari malformation and syringomyelia #2: Pathophysiological study and management of the disease oin craniovertebral junction Developmental Biology in the neural development and arteriosclerosis #1: Cephalic Neural Crest Cell Segregation and Migration #2: Molecular biological study of arteriosclerosis
PROFESSIONAL MEMBERSHIP
In Japan
Japan Neurosurgical Society, teaching board and delegate
Japan Neurosurgical Congress
Japanese Society of Spinal Surgery, teaching board and delegate
Japanese Society for Pediatric Neurosurgery
Japanese Society of Apoplexy Surgery
Japanese Society of Neurotrauma
In USA
Congress of Neurological Surgeon in USA,
Active International Member
American Association of Neurological Surgeons,
Active International Member
EXECUTIVE BOARD MEMBERSHIP
2005~
Review board of journal of the Japanese Society of
Spinal Surgery
2005
Osaka skull base and spine work-shop: director
2007
International hydrocephalus symposium
2008 ~
Medical advisory board of Chiari Syrinx Foundation (CSF)
2010
Kinki Spinal Surgery Society: director
2010
Kinki Neurosurgery Society: director
2014~
Director of Alumni of Neurosurgery, Osaka City University
2014
Executive Officer of Koudoukai Health System
2020
Executive Officer of Association of Osaka Prefecture Hospitals
Main professional publications Neuroscience
Naruhiko Nakanishi, Hiroaki Sakamoto, Misao Nishikawa, Akira Hakuba: Pathogenesis of encephaloschisis in retinoic-acid-treated hamster embryos I: a morphometric study of the craniofacial structures. Cranio Facial Anomaly 22: 1-10, 1999
Misao Nishikawa, Kiyoaki Tanaka, Mitsuhiro Hara: S: Cerebro-Spinal fluid flow: practice and absorption. Principles and Advances in Neurological Surgery Edit. Nobuo Hashimoto. Nakayama Ltd. (Tokyo) 1, pp 176-184, 2005
Misao Nishikawa, Akimasa Nishio, Ueda Makiko, Mitsuhiro Hara: Characterization of plaque in the internal carotid artery: comparison neuroradiological findings with pathological findings. Surgery for Cerebral Stroke 34: 199-205, 2006
Craniovertebral junction, spine and Pediatrics
Misao Nishikawa, Hiroaki Sakamoto, Akira Hakuba, Naruhiko Nakanishi, Yuichi Inoue: Pathogenesis of Chiari malformation: a morphometric study of the posterior cranial fossa. J Neurosurg 86: 40- 47, 1997
Hiroaki Sakamoto, Misao Nishikawa, Naruhiko Nakanishi, Akira Hakuba: Expansive suboccipital cranioplasty for the treatment of syringomyelia associated with Chiari malformation. Acta Neurochir (Wien) 141: 949-961, 1999
Misao Nishikawa, Hiroaki Sakamoto, Naruhiko Nakanishi Akira Hakuba: A clinical study on long-term outcome in patients with syringomyelia associated with Chiari malformation. Brain and Nerve 51: 318-323, 1999
Takeo Goto, Kenji Ohata, Toshihiro Takami, Misao Nishikawa: Prevention of postoperative posterior tethering of spinal cord after resection of ependymoma. J Neurosurg (Spine) 99- 181-187, 2003
Toshihiro Takami, Kenji Ohata, Misao Nishikawa, Takeo Goto, Yuzo Terakawa, Yuichi Inoue, Kenichi Wakasa, Mitsuhiro Hara: Transposition of occulomotor nerve for resection of a midbrain cavernoma. J Neurosurg 98: 913-916, 2003
Misao Nishikawa, Kenji Ohata, Motoki Baba, Yuzou Terakawa, Mitsuhiro Hara: fixation for Chiari I malformation associated with ventral compression and stability: one stage posterior decompression and fusion with a new instrumentation technique. Neurosurgery 54: 1430-1435, 2004
Misao Nishikawa, Kenji Ohata, Kenichi Ishibashi, Toshihiro Takami, Takeo Goto, Mistuhiro Hara. The anterolateral partial vertebrectomy approach for ventrally located cervical intramedullary cavernous angioma. Neurosurgery 59: 58-63, 2006
Thomas H. Milhorat, Paolo A. Bolognese, Misao Nishikawa et al: Syndrome of Occipitoatlantoaxial hypermobility, functional cranial settling and Chiari lformation I patients with hereditary disorders of connective tissue. J Neurosurg Spine 7: 601-609, 2007
Misao Nishikawa, Toshihiro Takami, Mitsuhiro Hara: Surgical Treatment for the OYL and CYL. Spine and Spinal cord disorders. Principles and Advances in Neurological Surgery Edit. Nobuo Hashimoto. Nakayama Ltd. (Tokyo) 11, pp 307-313, 2005
Misao Nishikawa, Kenji Ohata, Mitsuhiro Hara: Surgical Treatment for the disease at the craniovertebral junction. Spine and Spinal Cord disorders. Principles and Advances in Neurological Surgery Edit. Nobuo Hashimoto. Nakayama Ltd. (Tokyo) 11, pp 320-330, 2005
Milhorat, TM, Bolognese PA, Nishikawa M, McDonnell NB, Francomano CA: Association of Chiari malformation type I and tethered cord syndrome: preliminary results of sectioning filumn terminale. Surg Neurol 72: 20-35, 2009
Misao Nishikawa, Thomas H. Milhorat, Paolo A. Bolognese, Nazli B. McDonnell, Clair A. Francomano: Occipito-atlanto-axial hypermobility: clinical features and dynamic analysis of cranial settling and posterior gliding of occipital cindyle. Part 1: findings in patients with hereditary disorders of connective tissue and Ehlas-Danlos syndrome.Spinal Surgery 23: 168-175, 2009.
Misao Nishikawa, Thomas H. Milhorat, Paolo A. Bolognese, Nazli B. McDonnell, Clair A. Francomano: Occipito-atlanto-axial hypermobility: clinical features and dynamic analysis of cranial settling and posterior gliding of occipital cindyle. Part 2: findings in patients with post- traumatic condition. Spinal Surgery 23: 176-182, 2009.
Misao Nishikawa, Thomas H. Milhorat, Paolo A. Bolognese, Nazli B. McDonnell, Clair A. Francomano: Tethered cord syndrome: preliminary report of clinical features and morphometric analysis on association Chiari malformation type I. Spinal Surgery 23: 195-203,
Milhorat TH, Nishikawa M, Kula WR, Dlugacz DY. Mechanism of cerebellar tonsil herniation in patients with Chiari malformations as guide to clinical management. Acta Neurochir (Wien) May 04, 2011
Misao Nishikawa. Thomas H. Milhorat. Paolo A. Bolognese. Hiromichi Ikuno.Misao Pathogenesis and Management of Chiari malformations based on morphometric analyses of the posterior cranial fossa. Joural of Nurological Surgery Skull Base on line 0ct. 2019
Misao Nishikawa. Thomas H. Milhorat. Paolo A. Bolognese. Hiromichi Ikuno. Surgical management of Chiari malformation, according to the mechanism of hindbrainherniation. Joural of Nurological Surgery Skull Base on line 0ct. 2019
Misao Nishikawa. Paolo A. Bolognese,Toru Yamagata, Kentarou Naito, Hiroaki Sakamoto, Mistuhiro Hara, Kenji Ohata,5Takeo Goto. Surgical Management of Chiari Malformation Type I and Instability of the Craniocervical Junction Based on its Pathogenesis and Classification. Neurol Med Chir (Tokyo) 62: 400-415, 2022
Misao Nishikawa, Toru Yamagata, Kentarou Naito, Noritsugu Kunihiro, Hiroaki Sakamoto, Mistuhiro Hara. Kenji Ohata, Takeo Goto.Surgical Management of Chiari Malformation Type I Associated with Syringomyelia: Outcome of Surgeries Based on the new Classification and Study of Cerebrospinal Fluid Dynamics. J. Cli. Med 2022, 11, 4556
Misao Nishikawa, Hiroaki Sakamoto, Junsuke Katsuyama, Akira Hakuba, Shuro Nishimura: A case of multiple appearing and vanishing aneurysms: primary angiitis of the central nervous system. J Neurosurg 88: 133-137, 1998
Masaki Komiyama, Misao Nishikawa, Shouhei Kitano, et al: Transumbilical embolization of a congenital dural arteiovenous fistula at the torcular herophili in a neonate. J Neurosurg 90: 964-969, 1999
Toshihiro Yasui, Masaki Komiyama, Misao Nishikawa, Hideki Nakajima, Yasutsugu Kobayashi, Takeshi Inoue: Fusiform vertebral artery aneurysms as a cause of dissecting aneurysms. J Neurosurg 91: 139-144, 1999
Toshihiro Yasui, Masaki Komiyama, Misao Nishikawa, Hideki Nakajima: Subarachnoid hemorrhage from vertebral artery dissecting aneurysms involving the origin of the posterior cerebellar artery: report of two cases and review of the literature. Neurosurgery 46: 196-201, 2000
